HEALTH AND BIOLOGY

Overview

The activity “Magnetic biotechnologies” benefits from the know-how of the laboratory in magnetic materials, nanomagnetism, spin-electronics and nanofabrication. Our efforts are mainly focused towards the fabrication of engineered magnetic micro- nano-particles or devices, designed to apply forces on biological species. Their biomedical applications such as cancer cells destruction or stimulation of insulin production are investigated in collaboration with biology labs.

Research directions

Magnetic microdisks for cancer treatment

Magnetic microdisks for the destruction of targeted cancer cells induced by their low frequency mechanical vibrations (20 Hz) under alternating external magnetic field. (C.Naud et al, NANOSCALE ADVANCES, 2, 3632 (2020))

Arrays of flexible magnetic cantilevers

Arrays of flexible magnetic cantilevers used as micropumps, microswimmers or for magnetic field mapping thanks to their optical properties (A.Truong et al, Scientific reports 6 (2016) 31634)

The team

Former members

Post-docs

  • Caroline THÉBAULT(2018-2020)
  • Svetlana PONOMAREVA (2017-2019)
  • Alain TRUONG (2015-2017)

PhD

  • Cécile NAUD (2015-2018)

Projects

  • Projet IRGA MAGCELL 2021-2024 
  • NANOVIBER ANR/EURONANOMED 2017-2020
  • ABIOMATER, H2020 FET Open, 2015-2018
  • APOTRIG, Agir PEPS Univ. Grenoble Alpes, 2015-2016
  • Nano-Shark, ANR P2N, 2011-2016
  • Cible2012, Rhône-Alpes land, 2012-2015

 

Partners

  • Biomedial research center
    • BrainTech Lab   INSERM/UGA (targeted cancer cells and tumor destruction, in vitro & in vivo): François Berger (Neuro-oncologist, tumor nano-medicine), Matthieu Dreyfus.
  • Biology Laboratories
    • IRIG/SYMMES/LAN (toxicity, cancer cells, in vitro biological applications) Marie Carrière
    • IRIG/SYMMES/CREAB (surface biochemical functionalization) Yanxia Hou-Broutin
  • Microelectronics technology
    • LTM (Force microscopy on cells) Alice Nicolas

Recent news

  • Biocompatible magnetic microparticles for cancer cells destruction (February 04th, 2022)Biocompatible magnetic microparticles for cancer cells destruction
    We present a new type of biocompatible surface-functionalized magnetic microparticles for cancer cells destruction. The magnetite particles, covered with polyethylene glycol molecules, are shown to favor cell-death via apoptosis when set into vibrations by alternating ...
  • Seminar – Understanding cancer cell reactions to mechanical stress : towards new magnetism-based therapies (December 17th, 2021)Seminar - Understanding cancer cell reactions to mechanical stress : towards new magnetism-based therapies
    On Friday, January 14th at 11:00 Pr. François Berger BrainTech Lab Director Inserm and Univ. Grenoble Alpes will give us a seminar entitled: Understanding cancer cell reactions to mechanical stress : towards new magnetism-based therapies Place : ...
  • Masters thesis projects for Spring 2022 (September 17th, 2021)Masters thesis projects for Spring 2022
    You find here the list of proposals for Master-2 internships to take place at Spintec during Spring 2022. In most cases, these internships are intended to be suitable for a longer-term PhD work. Interested Master-1 ...
  • Highlights of SPINTEC research in 2020 (December 10th, 2020)Highlights of SPINTEC research in 2020
    The research highlights of SPINTEC over the year 2020 have been put together, and are available to download: https://www.spintec.fr/spintec-annual-booklets. This booklet contains the key facts of the lab over the period (contracts, new staff etc.), the ...
  • Masters thesis projects for Spring 2021 (September 15th, 2020)Masters thesis projects for Spring 2021
    You find here the list of proposals for Master-2 internships to take place at Spintec during Spring 2021. In most cases, these internships are intended to be suitable for a longer-term PhD work. Interested Master-1 ...

Publications


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