HEALTH AND BIOLOGY

Overview

The activity “Health and Biology” benefits from the know-how of the laboratory in magnetic materials, spin-electronics and nanofabrication. Our efforts are mainly focused towards the fabrication of engineered magnetic micro- nano- particles or devices, prepared by top-down approaches, specially designed for biomedical applications, such as cancer cells destruction triggering, tissue engineering.

Research directions

Magnetic particles for cancer treatment

particles
A biomedical application using anisotropic magnetic nanoparticles, aiming at the targeted destruction of cancer cells, by triggering their apoptosis / necrosis, thanks to the vibration of the particles attached to the membranes, in low magnetic fields of low frequency (~20 Hz).

Magnetic metamaterials for biological applications

metamaterials
Metamaterials, whose functionality is controlled by external magnetic fields, aiming at biological applications. The materials consist of micromotors or microtweezers, comprising ferromagnetic particle pairs embedded in a polymer matrix, and magneto-elastic membranes.

The team

Former members

Post-docs

  • Svetlana PONOMAREVA (2017-2019)
  • Alain TRUONG (2015-2017)

PhD

  • Cécile NAUD (2015-2018)

Projects

  • ABIOMATER, H2020 FET Open, 2015-2018
  • APOTRIG, Agir PEPS Univ. Grenoble Alpes, 2015-2016
  • Nano-Shark, ANR P2N, 2011-2016
  • Cible2012, Rhône-Alpes land, 2012-2015

Partners

  • Biomedial research center
    • CLINATEC Lab/INSERM/CHU/UGA (targeted cancer cells and tumor destruction, in vitro & in vivo): François Berger (Neuro-cancerologist, tumor nano-medicine), Matthieu Dreyfus.
  • Biology Laboratories
    • INAC/SYMMES/LAN (toxicity, cancer cells, in vitro biological applications) Marie Carrière
    • INAC/SYMMES/CREAB (surface biochemical functionalization) Yanxia Hou-Broutin
    • TheREx/TIMC-IMAG, CNRS UMR 5525 (cancer cells) Bertrand Toussaint
  • Microelectronics technology
    • LTM (Nanofabrication using block copolymer template) Ahmad Bsiesy, Thierry Baron
    • LTM (Microfluidics) David Peyrade

Recent news

  • Highlights of SPINTEC research in 2020 (December 10th, 2020)Highlights of SPINTEC research in 2020
    The research highlights of SPINTEC over the year 2020 have been put together, and are available to download: http://www.spintec.fr/spintec-annual-booklets. This booklet contains the key facts of the lab over the period (contracts, new staff etc.), the ...
  • Masters thesis projects for Spring 2021 (September 15th, 2020)Masters thesis projects for Spring 2021
    You find here the list of proposals for Master-2 internships to take place at Spintec during Spring 2021. In most cases, these internships are intended to be suitable for a longer-term PhD work. Interested Master-1 ...
  • Review — Cancer treatment by magneto-mechanical effect of particles (June 30th, 2020)Review -- Cancer treatment by magneto-mechanical effect of particles
    Cécile Naud, Caroline Thébault, Marie Carrière, Yanxia Hou, Robert Morel, François Berger, Bernard Dieny, Hélène Joisten, Nanoscale Advances, RSC (2020). Cancer treatment by magneto-mechanical effect of particles (TMMEP) is a growing field of research. The principle ...
  • Masters thesis projects for Spring 2020 (September 30th, 2019)Masters thesis projects for Spring 2020
    You find here the list of proposals for Master-2 internships to take place at Spintec during Spring 2020. In most cases, these internships are intended to be suitable for a longer-term PhD work. Interested Master-1 ...
  • Magnetic control of optical responses of biocompatible magneto-elastic membranes (August 29th, 2019)Magnetic control of optical responses of biocompatible magneto-elastic membranes
    Numerous studies investigated the use of synthetic membranes for photonic or biomedical applications. We report here on a recent type of biocompatible magnetically actuated membranes, partly originating from studies on magnetic particles for biology, consisting ...

Publications

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