HEALTH AND BIOLOGY

Overview

The activity “Health and Biology” benefits from the know-how of the laboratory in magnetic materials, spin-electronics and nanofabrication. Our efforts are mainly focused towards the fabrication of engineered magnetic micro- nano- particles or devices, prepared by top-down approaches, specially designed for biomedical applications, such as cancer cells destruction triggering, tissue engineering.

Research directions

Magnetic particles for cancer treatment

particles

A biomedical application using anisotropic magnetic nanoparticles, aiming at the targeted destruction of cancer cells, by triggering their apoptosis / necrosis, thanks to the vibration of the particles attached to the membranes, in low magnetic fields of low frequency (~20 Hz).

Magnetic metamaterials for biological applications

metamaterials

Metamaterials, whose functionality is controlled by external magnetic fields, aiming at biological applications. The materials consist of micromotors or microtweezers, comprising ferromagnetic particle pairs embedded in a polymer matrix, and magneto-elastic membranes.

The team

Permanent staff

JOISTEN

Hélène JOISTEN
helene.joisten@cea.fr

ID-MOREL
Robert MOREL
robert.morel@cea.fr
Bernard DIENY 041
Bernard DIENY
bernard.dieny@cea.fr

Post-docs

  • Alain TRUONG (2015-2017)

PhD

  • Cécile NAUD (2015-2018)

Projects

  • ABIOMATER, H2020 FET Open, 2015-2018
  • APOTRIG, Agir PEPS Univ. Grenoble Alpes, 2015-2016
  • Nano-Shark, ANR P2N, 2011-2016
  • Cible2012, Rhône-Alpes land, 2012-2015

Partners

  • Biomedial research center
    • CLINATEC Lab/INSERM/CHU/UGA (targeted cancer cells and tumor destruction, in vitro & in vivo): François Berger (Neuro-cancerologist, tumor nano-medicine), Matthieu Dreyfus.
  • Biology Laboratories
    • INAC/SYMMES/LAN (toxicity, cancer cells, in vitro biological applications) Marie Carrière
    • INAC/SYMMES/CREAB (surface biochemical functionalization) Yanxia Hou-Broutin
    • TheREx/TIMC-IMAG, CNRS UMR 5525 (cancer cells) Bertrand Toussaint
  • Microelectronics technology
    • LTM (Nanofabrication using block copolymer template) Ahmad Bsiesy, Thierry Baron
    • LTM (Microfluidics) David Peyrade

    Recent news

  • Nanotweezers and their remote actuation by magnetic fields (May 23rd, 2017)
    We have developed arrays of innovative magnetic nanotweezers or “nanojaws” on silicon wafers, by a top-down approach using the fabrication techniques of microelectronics. The mechanical manipulation of micro- and nanometric objects relies on constantly evolving techniques, ...
  • Magneto-optical micromechanical systems for magnetic field mapping (February 17th, 2017)
    Magnetic field mapping techniques have continuously been developed due to the necessity for determining the spatial components of local magnetic fields in many industrial applications and fundamental research. Several factors are considered for sensors such ...
  • 18 months post-doctoral position: Magnetically actuated metamaterials for biotechnology applications (January 30th, 2017)
    The SPINTEC and SyMMES laboratories of INAC (CEA-Grenoble), offer an 18 months post-doctoral position on the development of magnetically actuated metamaterials prototypes for biotechnology applications. This work is part of the ABIOMATER European FET project, ...
  • Proposals for student internships for Spring 2017 (November 26th, 2016)
    You find here the list of proposals for Master-2 internships to take place during Spring 2017. In most cases, these internships are intended to be suitable for a longer-term PhD work. You may either download the ...
  • Nanoviber – An ERA-NET project at SPINTEC (November 26th, 2016)
    Overview NANOVIBER (EURONANOMED-II ERA-NET project) was accepted at the Fall 2016. Context: Despite the progress of chemo-radiotherapy, molecular and cellular therapies as well as neurosurgery, glioblastoma remains a deadliness disease. Beside drugs, radiotherapy and surgery, “physical” therapies are ...

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